Antibacterial activity and Preliminary phytochemical screening of hot- aqua extract of Tetradenia riparia leaves
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Date
2014-08
Journal Title
Journal ISSN
Volume Title
Publisher
INTERNATIONAL JOURNAL OF PHARMACY & LIFE SCIENCES
Abstract
Nature is a paradise of medicinal solutions to all ailments affecting human beings. Medicinal plants have been used
widely to treat against the currently widespread strains of drug resistant bacteria. Green medicine has attracted great
interest due to the belief that it is safe, cheap and more dependable than aliphatic drugs, which have adverse side
effects. The current study was done to analyze the Phytochemical and antibacterial activity of hot – aqua extract of
Tetradenia riparia leaves. The Phytochemical results showed the plant to contain very important compounds (Table
1). The infused plant extract (Table 2) inhibited the growth of all the microorganisms tested. Bacillus cereus was the
microorganism which had the highest zone of inhibition of 22.67± 0.453, followed by Serratia liquefaciens with an
inhibition zone of 21.00±0.577, Enterobacter aerogenes inhibition zone of 14.33±0.333, Salmonella typhi,
13.33±0.333 and Escherichia coli, 13.33±0.887. Penicillin which was used as the positive control inhibited all the
microorganisms while dimethyl sulfoxide (DMSO) which was used was used as the negative control did not show
any zones of inhibition against the microorganisms used in the study. The results obtained in this study shows that
the plant’s potency in the treatment against all the bacterial organisms tested. However further research needs to be
done to isolate the active compounds, determine their structure, their mode of action and their effect in the in vivo
environment.