In Vitro Antibacterial activity of Ethanolic - aqua extract of Tagetes minuta leaves harvested from The University of Eastern Africa, Baraton, Nandi County, Kenya
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Date
2015-05
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Publisher
INTERNATIONAL JOURNAL OF PHARMACY & LIFE SCIENCES
Abstract
Tagetes minuta is a plant that has been used in traditional medicine for the treatment of various illnesses. In this
study, the ethanolic extract of T. minuta was tested for its antibacterial activity against selected microorganisms of
clinical significance. In an antibiotic susceptibility assay using the plant extract and DMSO control, the results from
the study showed that the extract was active against Proteus vulgaris with zone of inhibition of 17.30±0.333mm,
Escherichia coli 9.30±0.333mm, Salmonella typhi 11.83±0.44mm, Bacillus cereus 8.00±0.000 and Enterobacter
aerogenes 16.67±0.882mm. The penicillin positive control showed high zones of inhibition while the DMSO
negative control showed no zones of inhibition. An analysis of variance test on the results showed that there were
significant differences in the zones of inhibition of the extract and penicillin against all the organisms (p<0.0001).
These results have shown that the growth of these organisms can be controlled with the extract, hence making the
extract components potential agents for incorporation into drug production.