Antibacterial activity of Methanolic extracts of Cola nitida Seeds on Selected Pathogenic Organisms
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Date
2014
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Publisher
International Journal of Current Microbiology and Applied Sciences (IJCMAS)
Abstract
Cola nitida has been used in folk medicine and is a member of the family
Steculicca. The aim of the current study was to investigate the antibacterial activity
of Cola nitida. Antibacterial screening was done using agar well diffusion method
against Bacillus cereus, Serratia marcescens, Staphyloccus epidermidis, Proteus
vulgaris and Salmonella typhi. The results of antibacterial activity of red Cola
nitida showed a zone of inhibition of 23.67±0.882 on Bacillus cereus, 22.67±1.452
on Serratia marcescens, 24.33±0.667 on Staphyloccus epidermidis and
13.00±0.577 on Proteus vulgaris. The penicillin control showed large zones of
inhibition except for B. cereus and DMSO did not show any zones of inhibition.
The antibacterial property shown by the plant extracts is an evidence of the
ethnomedicinal uses of the plants. Incorporation of active compounds isolated from
the methanol extract of Cola nitida into conventional drug preparations can also
tackle the challenges posed by drug resistant microorganisms.