In Vitro control of selected pathogenic organisms by Vernonia adoensis roots
Loading...
Date
2013-08-01
Journal Title
Journal ISSN
Volume Title
Publisher
INTERNATIONAL JOURNAL OF PHARMACY & LIFE SCIENCES
Abstract
The main aim of conducting this study was to evaluate antibacterial activity of methanol–water extract of Vernonia
adoensis roots against Salmonella typi, Klebsiella sp, Bacillus cereus, Streptococcus pyogenes, E. coli, Proteus
vulgaris and Enterobacter aerogenes.The roots powder of the plant were extracted with methanol and water in the
ratio 9:1. The antibacterial activity of the extract was determined by agar well diffusion method. Vernonia adeonsis
roots extract was found to control the growth of only B. cereus, S. pyogenes and Proteus vulgaris at zone of
inhibition of 10.50 ± 0.563, 15.67 ± 0.422 and 11.00 ± 0.577 respectively. From the study methanol- water extract
can be used to control B. cereus, S. pyogenes and Proteus vulgaris. More research needs to be done to identify the
specific bioactive compounds, their structural formulas, their mode of action and toxicity in vivo conditions.