Browsing by Author "Jackie Obey K"

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    IN VITRO ANTIBACTERIAL ACTIVITY OF METHANOLIC – AQUA EXTRACT OF PLECTRANTHUS ARGENTATUS LEAVES
    (World Journal of Pharmaceutical research, 2013-11-23) Anthoney Swamy T; Jackie Obey K; Ngule Chrispus Mutuku
    The study was conducted to analyze the antibacterial activity of Plectranthus argentatus plant leaves. The plant sample was extracted using methanol and water in the ratio 9:1. From the study the plant Plectranthus argentatus was found to inhibit the growth of Escherichia coli with a zone of inhibition of 11.67 ± 0.882, Serratia liquefaciens zone of inhibition of 12.67 ± 0.667, Bacillus cereus 28.00 ± 1.154 and Proteus vulgaris 11.00 ± 0.577. The bacteria which had a zone of inhibition of less than 8 mm were termed to be unsusceptible. The data collected and documented in this paper is a scientific justification that the plant Plectranthus argentatus can be used to treat against various diseases caused by E.coli, S. liquefaciens, Bacillus cereus and Proteus vulgaris. However, more scientific data needs to be provided to indicate the mode action of the plant active compounds against the pathogens.
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    In Vitro Antibacterial activity of Methanolic-aqua extract of Tragia brevipes Leaves
    (2014-02) Anthoney SwamyT; Mutuku Chrispus Ngule; Jackie Obey K
    The plant Tragia brevipes is used traditionally as purgative and in the treatment of stomach problems, in the lower eastern part of Kenya. The aim of this research was to evaluate the antibacterial activities of the crude extract of Tragia brevipes leaves. The crude was extracted using methanol and water in the ratio of 9:1. Antibacterial activity was done using well diffusion methods and the data analysed using SPSS software to compare the means and also check whether there was significance between the zones of inhibitions caused by the plant extract and also those caused by the positive control. Tragia brevipes was found to inhibit the growth of Escherichia coli (12.00 ± 0.577), Salmonella sp. (10.33 ± 0.333), Enterobacter aerogenes (9.33 ± 0.333), Bacillus cereus (23.67 ± 0.882), Serratia liquefaciens (5.00 ± 2.646) and Proteus vulgaris (8.67 ± 0.333). The results obtained scientifically justify the traditional use of the plant to treat against enteric microbes such as Salmonella typhi and Enterobacter aerogenes. Tragia brevipes can be used as an antibiotic against all the microorganisms tested.